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Limitations of Current Evidence Several critical limitations characterize the current evidence base for these peptide therapeutics

Upon initiation of therapy, we found that the group of patients undertaking NAC exhibited significant increase in GSH levels and in total antioxidant status while displaying substantial reduction in lipid peroxidation compared to the control group

Previous research has demonstrated that xCT serves a crucial role in ferroptosis in certain cell types such as F98, 143B, BjeHLT, BJeLR, Calu-1 and HT-1080 cells (87,111)